Studies on Abnormal Hemoglobins

"Pseudo-abnormal" hemoglobins.

Abnormal Hemoglobins in Turkey.

The presence of HbS was reported in Turkey for the first time in the late fifties by Aksoy et al. This was followed by other reports by the same author revealing the presence of several other abnormal hemoglobins in Turkey. So far up to present 42 abnormal hemoglobins have been identified in the Turkish population. In addition to the studies conducted in Turkey, many European researchers report...

Studies on Invertebrate Hemoglobins (erythrocruorins)

1. Two high molecular invertebrate hemoglobins (the erythrocruorins of Lumbricus terrestris and of Nereis virens) as well as the low molecular erythrocruorin of Glycera dibranchiata Ehlers were studied. Their physical chemical properties were compared with those of vertebrate hemoglobin. 2. The hemin of the blood pigment of Glycera dibranchiata Ehlers was shown to be identical with that of vert...

Abnormal hemoglobins in a quarter million people.

Hemolysates of erythrocytes from more than a quarter million people in Alabama were electrophoresed on cellulose acetate, pH 8.4, and those samples exhibiting an abnormality were also electrophoresed in citrate agar, pH 6.0. The globin chains of mutants other than Hb S and C were electrophoresed in urea-mercaptoethanol buffers at both pH 8.9 and pH 6.0, and 60 of them were also analyzed structu...

Studies on Cobalt Myoglobins and Hemoglobins

The reversible oxygenation equilibrium of cobalt myoglobins and hemoglobins, complexes of apomyoglobin and apohemoglobin with cobaltous proto-, meso-, and deuteroporphyrins IX (proto-, meso-, and deutero-CoMb and -CoHb) has been investigated kinetically by the temperature jump relaxation method. The following association and dissociation rate constants (k,, and iz& were obtained in 0.1 M phosph...